个人简介
曹志婷，博士生导师，特聘副研究员，2013年毕业于四川大学高分子科学与工程学院，2018年获得中国科学技术大学理学博士学位，2018年-2020年在华南理工大学从事博士后研究，2020年12月加入中国药科大学生物药物学院。近年来，先后主持国家自然科学基金3项、广东省、江苏省自然科学基金2项，校级课题3项，横向项目4项，参与国家重点研发项目及省部级课题多项。近五年在Proc. Natl. Acad. Sci. U. S. A., Adv. Funct. Mater., Signal Transduction Targeted Ther., ACS Nano, Cell Death Dis., Biomaterials, Nano Res.等国际期刊发表SCI论文10余篇，两次担任J. Funct. Biomater.期刊客座编辑，为Signal Transduction Targeted Ther., Adv. Sci., Adv. Funct. Mater.等杂志审稿。获江苏省免疫学会青年委员，中国生物材料大会青年科学家等荣誉，参编中国药科大学研究生精品教材，本科生课程获评江苏省高校混合式精品通识课程，指导本科生获得江苏省大学生创业计划竞赛银奖，指导博士生获中美纳米会议论坛优秀墙报，指导硕士生获中国生物材料学会优秀墙报等。
研究方向
智能溶瘤微生物制剂开发；
工程化干细胞治疗体系构建；
创新口服生物大分子递送平台；
近年发表论文
Zhiting Cao†, Jianye Ren†, Yuguan Huang, Tong Li, Zhen Wang, Zhangyi Miao, Jia Jia, Yang Ding*.Engineered Iontophoresis Patch for Epicutaneous Allergen-specific Immunotherapy. Adv. Funct. Mater. 2025: e03522.
Huang B, Yin T, Fu S, Liu L, Yang C, Zhou L, Liu X, Zhuang H, Cao Z*, Hua Z*. Inflammation-oriented montmorillonite adjuvant enhanced oral delivery of anti-TNF-α nanobody against inflammatory bowel disease. Proc. Natl. Acad. Sci. U. S. A. 2024, 10, 121:e2320482121.
Shihui Yu#, Zhiting Cao#, Fangfang Cai, Yingying Yao, Xiaoyao Chang, Xiaoyang Wang, Hongqin Zhuang*, Zichun Hua*. ADT-OH exhibits anti-metastatic activity on triple-negative breast cancer by combinatorial targeting of autophagy and mitochondrial fission. Cell Death Dis., 2024, 15, 463.
Lina Liu, Xing Liu, Wenjie Xin, Lulu Zhou, Baolian Huang, Chao Han, Zhiting Cao*, Zichun Hua*. A bacteria-based system expressing anti-TNF-α nanobody for enhanced cancer immunotherapy. Signal Transduction Targeted Ther.,2023, 8: 134.
Fu, S.†, Cao, Z†., Huang, B. et al. Tannic acid assisted anti-TNF-α nanobody assembly modulating the epithelial barrier dysregulation of allergic rhinitis. Nano Res. 2023, 16, 9781–9791.
Gao M, Yang C, Wu C, Chen Y, Zhuang H*, Wang J*, Cao Z*. Hydrogel-metal-organic-framework hybrids mediated efficient oral delivery of siRNA for the treatment of ulcerative colitis. J. Nanobiotechnol., 2022 20(1):404.
Huang, Xin; Ren, Ke; Chang, Zhiyong; Ye, Youqing; Huang, Dechun; Zhao, Wei; Yang, Lixin; Dong, Yuqin; Cao, Zhiting*; Qiao, Haishi*; Glucose oxidase and L-arginine functionalized black phosphorus nanosheets for multimodal targeted therapy of glioblastoma, Chem. Eng. J., 2022, 430: 0-132898.
Yang Chen; Jia-Xian Li; Na Shu; Sui-Juan Zheng; Min Ma; Zhi-Bin Zhao; Zhi-Ting Cao*; Qi Zhou*; Jin-Zhi Du*; Jun Wang. A polymeric nanoformulation improves the bioavailability and efficacy of sorafenib for hepatocellular carcinoma therapy, Biomater. Sci., 2021, 9(7): 2508-2518.
Zhi-Ting Cao, Li-Qin Gan, Wei Jiang, Ji-Long Wang, Hou-Bing Zhang, Yue Zhang, Yucai Wang, Xianzhu Yang, Menghua Xiong*, Jun Wang*. Protein Binding Affinity of Polymeric Nanoparticles as a Direct Indicator of Their Pharmacokinetics. ACS Nano, 2020, 14(3): 3563-3575.
